Fridays in Skye 284
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Social Time: 1:30-2:00pm
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Talk: 2:00-2:50pm
Abstract pending
Advisor: Wee Liang Gan
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Advisor: Dr. Jia Gou
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Advisor: Dr. Yiwei Wang
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Advisor: Dr. Jose Gonzalez
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Advisor: Dr. Michel Lapidus
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Advisor: Wee Liang Gan
We'll cover what are real Lie groups, some definitions regarding restricted roots, and their role in what a positive structure is. First, we will look at the inspiration of these constructions and they have been extended to semisimple real Lie groups. We'll cover some examples, and we will give arguments why these can't appear in the context of complex Lie groups.
Advisor: Brian Collier
Robust organ formation depends on the coordinated regulation of cellular mechanics, yet how mechanobiological processes such as controlled cell-cell and cell-matrix adhesion, actomyosin contractility, membrane stiffness, and internal pressure interlink to generate an organ’s architecture remains poorly understood. Here, we systematically investigated underlying mechanobiology principles using Drosophila wing disc eversion, the metamorphic conversion of a larval epithelial sac into a functional wing. By integrating quantitative imaging experiments with a novel nonlinear physics informed multiscale computational model (PIMM), we extensively tested the roles of individual drivers of tissue morphogenesis, as well as their different combinations. Our analysis suggests the following multi-level sequence of morphogenetic processes defining early wing metamorphosis. First, the localized detachment of the basal ECM at the dorsal-ventral compartment boundary initiates folding and boundary forces rotate and shear the wing disc pouch to guide the proximal ends of the pouch together. Then, patterned actomyosin contractility closes the fold. Also, cell rearrangements promote tissue elongation all through the process. In sum, these results show how organogenesis relies on a combination of subcellular force-generation mechanisms and tissue-level deformations. The developed integrated, data-calibrated nonlinear PIMM framework can serve as a versatile general tool for investigating the mechanisms of tissue development and regeneration.
Advisor: Dr. Mark Alber
The UC Riverside Math Graduate Student Seminar (GSS) is brought to you by the UCR student chapter of the American Mathematics Society. GSS is organized by the officers of the chapter.
David Weed, President
Cynthia Nguyen, Secretary
Max Klivans, Treasurer